Multidrug-Resistant Shigella sonnei Bacteremia among Persons Experiencing Homelessness, Vancouver, British Columbia, Canada

Increased invasive bloodstream infections caused by multidrug resistant Shigella sonnei were noted in Vancouver, British Columbia, Canada, during 2021-2023. Whole-genome sequencing revealed clonal transmission of genotype 3.6.1.1.2 (CipR.MSM5) among persons experiencing homelessness. Improvements in...

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Veröffentlicht in:	Emerging infectious diseases 2023-08, Vol.29 (8), p.1668-1671
Hauptverfasser:	Stefanovic, A, Matic, N, Ritchie, G, Lowe, C F, Leung, V, Hull, M, Alam, M, Dawar, M, Champagne, S, Romney, M G
Format:	Artikel
Sprache:	eng
Schlagworte:	Anti-Bacterial Agents - pharmacology Anti-Bacterial Agents - therapeutic use Antimicrobial agents antimicrobial resistance Bacteremia Bacteremia - drug therapy Bacteremia - epidemiology Bacteremia among Persons Experiencing Homelessness, Vancouver, British Columbia, Canada bacteria British Columbia - epidemiology Causes of Dispatch Drug resistance Drug resistance in microorganisms Drug Resistance, Multiple, Bacterial - genetics Dysentery, Bacillary - drug therapy Dysentery, Bacillary - epidemiology E coli enteric infections Feces Genotype & phenotype Health aspects Homeless people Homeless persons Homelessness Hospitalization Hospitals Humans Identification and classification Ill-Housed Persons Infections Laboratories Literature reviews Microbial Sensitivity Tests Multidrug resistant organisms Multidrug-Resistant Patients Public health Sanitation Sepsis Serology Shigella Shigella sonnei Shigella sonnei - genetics Shigellosis Statistics Surveillance Trends
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Zusammenfassung:	Increased invasive bloodstream infections caused by multidrug resistant Shigella sonnei were noted in Vancouver, British Columbia, Canada, during 2021-2023. Whole-genome sequencing revealed clonal transmission of genotype 3.6.1.1.2 (CipR.MSM5) among persons experiencing homelessness. Improvements in identifying Shigella species, expanding treatment options for multidrug resistant infections, and developing public health partnerships are needed.
ISSN:	1080-6040 1080-6059
DOI:	10.3201/eid2908.230323