Synthetic hydroxyapatite and its use in bioactive coatings

An approach to solve the limitations of autologous bone grafting procedures in bone injury treatment is to develop bioactive coatings in the implantation system. The objective of this work is to compare the temperature effect on the stability of hydroxyapatite, graphene, and collagen colloidal suspensions to be used as biocompatible and bioactive coatings on a carbon fiber composite surface. Synthesized hydroxyapatite was assessed by X-ray diffraction. Zeta potential at different temperatures was evaluated. Specimens were characterized using scanning electron microscopy and Raman analysis. The results showed that the best hydroxyapatite/graphene ratio was 85/15, while those of the hydroxyapatite/collagen mixtures were 85/15. A hydroxyapatite/graphene/collagen mixture was synthesized based on these results.