A Case with Laron Syndrome

A Case with Laron Syndrome

Laron syndrome (LS) is a rare disorder leading to short stature as a result of growth hormone (GH) insensitivity. It is caused by mutations in GH receptor gene and characterized by post-natal growth retardation, craniofacial abnormalities, high serum GH and low insulin-like growth factor-I (IGF-I) l...

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Veröffentlicht in:Bezmialem Science 2019-07, Vol.7 (3), p.251-254
Hauptverfasser: ÖZGEN, İlker Tolga, KUTLU, Esra, CESUR, Yaşar, YEŞİL, Gözde
Format: Artikel
Sprache:eng
Schlagworte:
Age
Birth weight
Children & youth
Codon
Conflicts of interest
Gene mutations
Genetic aspects
Genotype & phenotype
Growth hormone insensitivity
Growth hormones
Hypoglycemia
Insulin
insulin-like growth factor-I therapy
Insulin-like growth factors
Intellectual disabilities
Laboratories
Laron syndrome
Mutation
Obesity
Parents & parenting
Patients
Protein binding
short stature
Somatotropin
Tıp
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Beschreibung
Zusammenfassung:Laron syndrome (LS) is a rare disorder leading to short stature as a result of growth hormone (GH) insensitivity. It is caused by mutations in GH receptor gene and characterized by post-natal growth retardation, craniofacial abnormalities, high serum GH and low insulin-like growth factor-I (IGF-I) levels. Several different genetic mutations have been documented up to date. In this article, a patient with LS is reported. A 2-year-old female patient was admitted to the hospital with the complaint of short stature. Her height and weight was 71.7 cm [
ISSN:2148-2373
2148-2373
DOI:10.14235/bas.galenos.2018.2385