Biomimetic nanomedicines for precise atherosclerosis theranostics

Atherosclerosis (AS) is a leading cause of the life-threatening cardiovascular disease (CVD), creating an urgent need for efficient, biocompatible therapeutics for diagnosis and treatment. Biomimetic nanomedicines (bNMs) are moving closer to fulfilling this need, pushing back the frontier of nano-ba...

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Veröffentlicht in:Acta pharmaceutica Sinica. B 2023-11, Vol.13 (11), p.4442-4460
Hauptverfasser: Tao, Ying, Lan, Xinmiao, Zhang, Yang, Fu, Chenxing, Liu, Lu, Cao, Feng, Guo, Weisheng
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Sprache:eng
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Zusammenfassung:Atherosclerosis (AS) is a leading cause of the life-threatening cardiovascular disease (CVD), creating an urgent need for efficient, biocompatible therapeutics for diagnosis and treatment. Biomimetic nanomedicines (bNMs) are moving closer to fulfilling this need, pushing back the frontier of nano-based drug delivery systems design. This review seeks to outline how these nanomedicines (NMs) might work to diagnose and treat atherosclerosis, to trace the trajectory of their development to date and in the coming years, and to provide a foundation for further discussion about atherosclerotic theranostics. This review summerize various biomimetic nanomedicines for precise atherosclerosis diagnosis and treatment, which is vital for the development of atherosclerotic theranostic agents. [Display omitted]
ISSN:2211-3835
2211-3843
DOI:10.1016/j.apsb.2022.11.014