Sickle Cell Trait and Kidney Disease in People of African Ancestry With HIV

Sickle cell trait (SCT) has been associated with chronic kidney disease (CKD) in African Americans, although evidence for its impact in Africans and people with HIV is currently lacking. We conducted a cross-sectional study investigating the association between SCT and kidney disease in people of Af...

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Veröffentlicht in:	Kidney international reports 2022-03, Vol.7 (3), p.465-473
Hauptverfasser:	Hung, Rachel K.Y., Hilton, Rachel, Hamzah, Lisa, Burns, James E., Kegg, Stephen, Onyango, Denis, Santana-Suarez, Beatriz, Campbell, Lucy, Sharpe, Claire C., Sabin, Caroline A., Winkler, Cheryl A., Booth, John, Hand, James, Murphy, Maurice, Clarke, Amanda, Richardson, Celia, Barbour, Lisa, Kennard, Vicky, Trevitt, Vittorio, Levy, Jeremy, Rabuya, May, Uzu, Hiromi, Williams, Karen, Mahiouz, Karina, Cheetham, Tess, Thomas, Caroline, Doctor, Jessica, Berlanga, Andrea, Wandolo, Emily, Appleby, Tim, Driver, Lois, Parr, Sophy, Crowe, Andrew, Boateng, Vida, Klein, Marie-Pierre, Buckingham, Christian, Trotman, Daniel, Quinn, Killian, Flanagan, Kate, Middleditch, Holly, Samuel, Itty, Canoso, Ana, Agbasi, Emeka, Minton, Jane, Lamont, Gary, Saiyad, Gaushiya, Ahmed, Shadia, Murira, J., Phyu, Khine, Shaw, Jonathan, Holland, Sarah, George, Valerie, Lambert, Pauline, Lukha, Hinal, Vora, Nina, Price, David Ashley, Stothard, Tara, McVittie, Ian, Kennedy, Ciara, Shwab, Uli, Payne, Brendan, Duncan, Sarah, Dixon, Jill, Schmid, Mathias, Duncan, Christopher, Hunter, Ewan, Astill, Natasha, Winkler, Cheryl, Binns-Roemer, Elizabeth, David, Victor, Vincent, Rachel, Saad, Chloe, Azzoug, Hocine, Mabonga, Emily, Larbi, W., Burns, Fiona, Ngwu, Nnenna, Edwards, Jonathan, Ferro, Filippo, Nogueira, Pedro, Mutagwanya, Victoria, Cosgrove, Catherine, Isitt, Catherine Emily, Popoola, Joyce, Mencias, Mark, Ramkhelawn, Rajeshwar, Lara, Sandra Oliva, Sajijad, Sara, Winston, Alan, Shaw, Amber, Ring, Kyle, Rosenvinge, Melanie, Odong, Faith, Ibe, Tina, Hill, Teresa
Format:	Artikel
Sprache:	eng
Schlagworte:	Africa APOL1 Clinical Research HIV kidney SCT sickle cell trait
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Zusammenfassung:	Sickle cell trait (SCT) has been associated with chronic kidney disease (CKD) in African Americans, although evidence for its impact in Africans and people with HIV is currently lacking. We conducted a cross-sectional study investigating the association between SCT and kidney disease in people of African ancestry with HIV in the UK. The primary outcome was estimated glomerular filtration rate (eGFR)
ISSN:	2468-0249 2468-0249
DOI:	10.1016/j.ekir.2021.12.007