DEPENDENCE OF THE DEVELOPMENT OF HISTOLOGICAL CHANGES IN THE TISSUES OF THE FALLOPIAN TUBES IN ADOLESCENT GIRLS AND YOUNG WOMEN WITH INFLAMMATORY GENITAL DISEASE ON THE TAXONOMIC AFFILIATION OF PATHOGENS

The aim. To conduct a comparative analysis of the fallopian tubes' clinical, microbiological and histological characteristics in adolescent girls and young women with inflammatory genital disease. Materials and methods. The etiological diagnosis of inflammatory disease was established with the help of complex microbiological and cytological studies of biomaterial from the vagina of teenage girls and the cervical canal of young women before hospitalization and histological examination fragments of fallopian tube – after surgery. The microbiological examination included the cultural detection of bacteria of various taxonomic groups, fungi, mycoplasmas, and ureaplasmas from the biomaterial. A set of methods described in the article was used to detect chlamydia [13]. The degree of bacterial infection of the fallopian tube fragments was assessed by determining the microbial count. Histological examination of biopsy specimens of fallopian tube tissues removed during surgery was performed by the conventional method [9]. Results. In the examination of 29 adolescent girls and young women hospitalized for surgical treatment, a comparative analysis was conducted between the clinical manifestations of inflammatory genital disease, identifiable factors, and histological signs of damaged fallopian tubes.When studying the spectrum of factors in the inflammatory focus (fallopian tube biopsies) in adolescent girls (n=12), enterobacteria (33.3%), staphylococci (33.3%), streptococci (8.35%), and Pseudomonas aeruginosa (8.35%) were detected; in 16.7% of adolescent girls, the cultures were sterile. In young women (n=17), microbiological examination of fallopian tube tissues revealed chlamydia (29.4%), mycoplasma (11.6%), ureaplasma (5.8%), gonococci (5.8%), enterobacteria (5.8%), fungi (5.8%); in 6 (35.8%) of the examined women, no bacterial growth was detected. Among young women who had been operated on for tubo-ovarian inflammatory diseases and ectopic pregnancy, chlamydia were most often (29.4%) found in the tissues of the fallopian tubes. Conclusions. The studies have shown that in the development of acute purulent salpingitis in young women, sclerotic changes and signs characteristic of the productive process prevailed in the tissues of the fallopian tubes against the background of genital inflammation, and in adolescent girls, an exudative process was observed against the background of genital inflammation. The peculiarities of the course of genital inflammation depend o