Indonesian prostate cancer risk calculator (IPCRC): an application for predicting prostate cancer risk (a multicenter study)

to develop a prediction risk model of prostate cancer based on Indonesia population. we included all benign prostate hyperthrophy (BPH) and PCa patients who had prostate biopsy and prostatectomy between January 2009 and December 2013 from 5 urology centers in Indonesia. The relationship between the...

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Veröffentlicht in:Acta medica Indonesiana 2015-04, Vol.47 (2), p.95-103
Hauptverfasser: Yuri, Prahara, Wangge, Grace, Abshari, Fatan, Satjakoesoemah, Adistra I T W H, Perdana, Noor R, Wijaya, Candra D K, Tansol, Christiano, Tigor, Aaron, Safriadi, Ferry, Kadar, Dhiraya D, Warli, Syah M, Rochadi, Sungsang, Danarto, Hakim, Lukman, Djatisoesanto, Wahjoe, Hardjowijoto, Sunaryo, Mochtar, Chaidir A, Umbas, Rainy, Hamid, Agus Rizal A H
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Sprache:eng
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Zusammenfassung:to develop a prediction risk model of prostate cancer based on Indonesia population. we included all benign prostate hyperthrophy (BPH) and PCa patients who had prostate biopsy and prostatectomy between January 2009 and December 2013 from 5 urology centers in Indonesia. The relationship between the possibility of PCa with the following variables including: age; PSA level, prostate volume (by transabdominal ultrasound or transrectal ultrasound) and digital rectal examination (DRE) finding. We calculated a predictive scoring equation to predict the possibility of PCa using chi-square analysis, Kolmogorov-Smirnov test, multiple logistic regression and ROC curve. Then, we designed an application for predicting prostate cancer risk called Indonesian Prostate Cancer Risk Calculator (IPCRC). there were 784 PCa and 1173 BPH patients were used for developing the risk calculator in our study. The mean ages, PSA and prostate volume are 66.9±8.1 years old; 72.4±248.9 ng/ml and 49.6±28.2 ml, respectively. Abnormal DRE was found in 637 PCa and 56 BPH. We included age, PSA level, abnormal DRE finding (all showed significant p
ISSN:0125-9326
2338-2732