Stability Study of Morphine and Baclofen Solution in Polypropylene Syringes

Stability Study of Morphine and Baclofen Solution in Polypropylene Syringes

The association of morphine and baclofen is used for the treatment of spasticity related pain. Moving these patients is sometimes difficult. In order to transport these syringes for pump refilling, it could be interesting to demonstrate the stability of the mixture, and so to be able to ensure the b...

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Veröffentlicht in:Pharmaceutical technology in hospital pharmacy 2017-12, Vol.2 (4), p.173-180
Hauptverfasser: Robert, Julien, Sorrieul, Jérémy, Kieffer, Hélène, Folliard, Caroline, Gibory, Vincent, Dupoiron, Denis, Devys, Catherine
Format: Artikel
Sprache:eng
Schlagworte:
baclofen
ICH
Morphine
polypropylene syringe
stability indicating method
UPLC DAD
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Zusammenfassung:The association of morphine and baclofen is used for the treatment of spasticity related pain. Moving these patients is sometimes difficult. In order to transport these syringes for pump refilling, it could be interesting to demonstrate the stability of the mixture, and so to be able to ensure the best transport conditions of syringes.
ISSN:2365-2411
2365-242X
DOI:10.1515/pthp-2017-0028