Transient abnormal myelopoiesis: A case series and review of the literature

Transient abnormal myelopoiesis: A case series and review of the literature

Transient abnormal myelopoiesis (TAM) is a rare and unique disorder affecting Down syndrome (DS) newborns. This case series presents 5 cases of Down syndrome with TAM diagnosed during 2007–2015 with detailed analysis of immunophenotypic data of each case. CD34, CD13, CD33, CD117, CD41, CD61, CD7 and...

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Veröffentlicht in:Pediatric hematology oncology journal 2017-03, Vol.2 (1), p.14-18
Hauptverfasser: Baloda, Vandana, Subramanian, Papagudi G., Badrinath, Yajamanam, Kumar, Ashok, Amare, Pratibha S. Kadam, Banavali, Shripad D., Arora, Brijesh, Gujral, Sumeet
Format: Artikel
Sprache:eng
Schlagworte:
Down syndrome
Immunophenotype
Transient abnormal myelopoiesis
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Zusammenfassung:Transient abnormal myelopoiesis (TAM) is a rare and unique disorder affecting Down syndrome (DS) newborns. This case series presents 5 cases of Down syndrome with TAM diagnosed during 2007–2015 with detailed analysis of immunophenotypic data of each case. CD34, CD13, CD33, CD117, CD41, CD61, CD7 and HLA-DR are useful markers for characterization of blasts of TAM.
ISSN:2468-1245
2468-1245
DOI:10.1016/j.phoj.2017.06.001