Beneficial and Safety Properties of a Bacteriocinogenic and Putative Probiotic Latilactobacillus sakei subsp. sakei 2a Strain

This work aimed to evaluate some of the probiotic features and safety of the bacteriocin-producing subsp. 2a. The effect of selected commercial drugs from different generic groups and antibiotics on the growth of subsp. 2a was also determined. The presence of virulence factors was determined based o...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Veröffentlicht in:Foods 2024-11, Vol.13 (23), p.3770
Hauptverfasser: Lipilkina, Tatiana Alexandrovna, Xu, Cristhian, Barbosa, Matheus de Souza, Khramova, Valentina Nikolaevna, Shebeko, Sergei K, Ermakov, Alexey M, Ivanova, Iskra Vitanova, Todorov, Svetoslav Dimitrov
Format: Artikel
Sprache:eng
Schlagworte:
Online-Zugang:Volltext
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
Beschreibung
Zusammenfassung:This work aimed to evaluate some of the probiotic features and safety of the bacteriocin-producing subsp. 2a. The effect of selected commercial drugs from different generic groups and antibiotics on the growth of subsp. 2a was also determined. The presence of virulence factors was determined based on PCR with total DNA from subsp. 2a. Good growth of subsp. 2a was recorded in MRS broth supplemented with 0.2% or 0.4% oxbile or in MRS broth adjusted to a pH from 5.0-9.0. Auto-aggregation of subsp. 2a was 62.59%. Different levels of co-aggregation were recorded between subsp. 2a and ATCC19443, ATCC15521 and ScottA. Growth of subsp. 2a was not inhibited by commercial drugs from different generic groups. The inhibitory effect on the growth of subsp. 2a was recorded only in the presence of Arotin [selective serotonin reuptake inhibitor antidepressant] Minimal Inhibition Concentration (MIC) 1.0 mg/mL, Atlansil [Antiarrhythmic] MIC 0.625 mg/mL, Diclofenac potassium [non-steroidal anti-inflammatory drug (NSAID)] MIC 2.5 mg/mL and Spidufen [NSAID] MIC 15.0 mg/mL. Only two antibiotics tested in this study, Amoxil and Urotrobel, inhibited the growth of subsp. 2a with a MIC of
ISSN:2304-8158
2304-8158
DOI:10.3390/foods13233770