Identification of Novel Mutations in the N Gene of SARS-CoV-2 That Adversely Affect the Detection of the Virus by Reverse Transcription-Quantitative PCR

Accurate and timely diagnosis of SARS-CoV-2 is a critical step toward controlling the viral spread, since it facilitates the identification and isolation of infected individuals. Mutations in the primer-/probe-binding sites may lead to false-negative results.

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Bibliographische Detailangaben
Veröffentlicht in:	Microbiology spectrum 2021-09, Vol.9 (1), p.e0054521-e0054521
Hauptverfasser:	Hasan, Rashedul, Hossain, Mohammad Enayet, Miah, Mojnu, Hasan, Md Mahmudul, Rahman, Mustafizur, Rahman, Mohammed Ziaur
Format:	Artikel
Sprache:	eng
Schlagworte:	Clinical Microbiology COVID-19 Letter to the Editor mutation N gene RT-qPCR SARS-CoV-2
Online-Zugang:	Volltext
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Beschreibung
Zusammenfassung:	Accurate and timely diagnosis of SARS-CoV-2 is a critical step toward controlling the viral spread, since it facilitates the identification and isolation of infected individuals. Mutations in the primer-/probe-binding sites may lead to false-negative results.
ISSN:	2165-0497 2165-0497
DOI:	10.1128/Spectrum.00545-21