1-{[5-(4-Chloro-phen-yl)-1-(4-fluoro-phen-yl)-1H-pyrazol-3-yl]carbon-yl]}piperidin-4-one

In the title compound, C(21)H(17)ClFN(3)O(2), the 1H-pyrazole ring makes dihedral angles of 36.73 (7), 18.73 (7) and 60.88 (8)°, respectively, with the mean planes of the chloro-phenyl, 4-oxo-piperidine and fluoro-phenyl rings. The mol-ecular structure is stabilized by an intra-molecular C-H⋯N hydro...

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Veröffentlicht in:Acta crystallographica. Section E, Structure reports online Structure reports online, 2010-12, Vol.66 (Pt 12), p.o3233-o3234
Hauptverfasser: Shahani, Tara, Fun, Hoong-Kun, Ragavan, R Venkat, Vijayakumar, V, Venkatesh, M
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Sprache:eng
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Zusammenfassung:In the title compound, C(21)H(17)ClFN(3)O(2), the 1H-pyrazole ring makes dihedral angles of 36.73 (7), 18.73 (7) and 60.88 (8)°, respectively, with the mean planes of the chloro-phenyl, 4-oxo-piperidine and fluoro-phenyl rings. The mol-ecular structure is stabilized by an intra-molecular C-H⋯N hydrogen bond, which forms an S(6) ring motif. In the crystal, inter-molecular C-H⋯O hydrogen bonds link mol-ecules into chains along [101]. In addition, inter-molecular C-H⋯F hydrogen bonds with an R(2) (1)(7) ring motif connect neighbouring chains into layers parallel to the ac plane.
ISSN:1600-5368
1600-5368
DOI:10.1107/S1600536810047215