Bullous vesicant-type reaction to docetaxel along the venous tract: A case report

•Docetaxel is typically considered an irritant, rather than a vesicant.•A patient experienced a bullous vesicant-type reaction after infusion without obvious extravasation.•Conservative management with steroids was successful in managing this case. Docetaxel is an anti-neoplastic agent commonly used to treat major solid tumors. Common toxicities of docetaxel include neutropenia, alopecia, nausea and vomiting. While docetaxel is typically considered an irritant, we present the case report of a 54-year-old female with high-grade undifferentiated uterine sarcoma who experienced a standard infusion reaction during a docetaxel infusion, followed by an atypical, delayed vesicant-type reaction, without a clear extravasation history.