The effect of vitamin D intake with chitosan coating along with six weeks of resistance training and on the antioxidant defense indices of the hippocampal tissue of ovariectomized rats

Background: Menopause is a process that occurs with the permanent cessation of ovarian function in women and has many complications. This study aimed to investigate the effect of vitamin D with chitosan coating along with six weeks of resistance training on the antioxidant indices of the hippocampal tissue of ovariectomized rats. Materials and Methods: 24 rats were randomly divided into 4 groups of 6. After ovariectomy, rats were divided into menopausal chitosan-coated vitamin D groups, menopausal exercise group, chitosan-coated vitamin D group and menopausal exercise, and menopausal control group. The training group did resistance training 5 days a week for 6 weeks. 24 hours after the last training session, the hippocampus was separated from the brain and the amounts of succinate dehydrogenase (SOD), malondialdehyde (MDA) and total antioxidant capacity (TAC) were measured by ELISA technique. To compare the groups, one-way ANOVA test was used at the alpha level of 0.05. Results: SOD values were significantly higher in the chitosan-coated vitamin D exercise group than the chitosan-coated vitamin D and menopausal control groups (P