Diffusion weighted MRI of mediastinal masses: Can measurement of ADC value help in the differentiation betw

Purpose: The purpose of this study is to evaluate the role of measurement of ADC value in the differentiation between benign and malignant mediastinal lesions. Patients and methods: 42 patients with 52 mediastinal lesions were included in this study. They underwent diffusion weighted MRI with b values of 1000 and 0 s/mm2. ADC value measurement and histopathological diagnosis were done for each lesion. Correlation between ADC value and histopathology was done through statistical analysis. Results: 32 lesions were malignant and 20 lesions were benign. The mean ADC value for the malignant lesions was significantly lower than the mean ADC value for benign lesions (P value