Association of interleukin-17A rs2275913 polymorphism with rheumatoid arthritis susceptibility in Sudanese population

Association of interleukin-17A rs2275913 polymorphism with rheumatoid arthritis susceptibility in Sudanese population

Objectives: Rheumatoid arthritis is a chronic inflammatory autoimmune disease. This study aimed to determine the association of interleukin-17A-197G/A polymorphism with rheumatoid arthritis in Sudanese patients. Methods: A case–control study was conducted between March and December 2018. Clinical an...

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Veröffentlicht in:SAGE open medicine 2021, Vol.9, p.20503121211020207-20503121211020207
Hauptverfasser: Osman, Rgda Mohamed, Noma, Mounkaila, Ahmed, Abdallah Elssir, Abdelbagi, Hanadi, Omer, Rihab Ali, Ali, Musab M, Mohammed Alameen, Ayman Ali, Edris, Ali Mahmoud, Muneer, Mohamed S., Siddig, Omayma, Hassan, Rowa, Ahmed, Eiman Siddig, Hassan, Lamis Ahmed, Bakheet, Osama El Hadi, Ahmed, Ayman, Mohamed, Nouh Saad, Siddig, Emmanuel Edwar
Format: Artikel
Sprache:eng
Schlagworte:
Confidence intervals
Cytokines
Original
Polymorphism
Rheumatoid arthritis
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Zusammenfassung:Objectives: Rheumatoid arthritis is a chronic inflammatory autoimmune disease. This study aimed to determine the association of interleukin-17A-197G/A polymorphism with rheumatoid arthritis in Sudanese patients. Methods: A case–control study was conducted between March and December 2018. Clinical and demographic data of the study participants were collected and analyzed. Polymerase chain reaction restriction fragment length polymorphism molecular technique was done to investigate interleukin-17A-197G/A polymorphisms. All statistical tests were considered statistically significant when p 
ISSN:2050-3121
2050-3121
DOI:10.1177/20503121211020207