A new therapeutic strategy for lung tissue injury induced by influenza with CR2 targeting complement inhibitior

Influenza is a respiratory disease that seriously threatens human health. In fact, influenza virus itself does not make critical contribution to mortality induced by influenza, but "cytokine storm" produced by the excessive immune response triggered by the virus can result in inflammatory reaction of lung tissues and fatal lung tissue injury, and thus increase influenza mortality. Therefore, besides antiviral drugs, immunosuppression drugs should also be included in infection treatment. CR2 targeting complement inhibitors are expected to be ideal drugs for viral pneumonia.