How prevalent is Plasmodium malariae in Rondônia, western Brazilian Amazon?

We have compared results of Plasmodium species identification obtained with conventional on-site microscopy of Giemsa-stained thick smears (GTS) and a semi-nested polymerase chain reaction (PCR) in 96 malaria patients from Rondônia, Western Brazilian Amazon. Mixed-species infections were detected by...

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Veröffentlicht in:	Revista da Sociedade Brasileira de Medicina Tropical 2000-10, Vol.33 (5), p.489-492
Hauptverfasser:	Cavasini, M T, Ribeiro, W L, Kawamoto, F, Ferreira, M U
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Brazil Brazilian Amazon Humans Malaria Malaria - epidemiology Malaria diagnosis PCR Plasmodium malariae Prevalence TROPICAL MEDICINE Vector-borne diseases
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Beschreibung
Zusammenfassung:	We have compared results of Plasmodium species identification obtained with conventional on-site microscopy of Giemsa-stained thick smears (GTS) and a semi-nested polymerase chain reaction (PCR) in 96 malaria patients from Rondônia, Western Brazilian Amazon. Mixed-species infections were detected by PCR in 30% patients, but no such case had been found on GTS. Moreover, P. malariae infections were detected in 9 of 96 patients (10%) by PCR, but were not identified by local microscopists. The potential impact of species misidentification on malaria treatment and control is discussed.
ISSN:	0037-8682 1678-9849 0037-8682 1678-9849
DOI:	10.1590/S0037-86822000000500011