Fecal Microbiota Transplantation for Severe Infant Botulism, China

Infant botulism in a 4-month-old boy in China who continued to excrete toxins for over a month despite antitoxin therapy was further treated with fecal microbiota transplantation. After treatment, we noted increased gut microbial diversity and altered fecal metabolites, which may help reduce intesti...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	Emerging infectious diseases 2024-08, Vol.30 (8), p.1732-1734
Hauptverfasser:	Fan, Chaonan, Li, Rubo, Wang, Lijuan, Li, Kechun, Jia, Xinlei, Gao, Hengmiao, Zhang, Bike, Xu, Xuefang, Qian, Suyun
Format:	Artikel
Sprache:	eng
Schlagworte:	Antitoxins Babies Bile Bioassays Botulism Botulism - microbiology Botulism - therapy Care and treatment Case studies Children & youth China Clostridium botulinum Diseases Fecal Microbiota Transplantation Fecal Microbiota Transplantation for Severe Infant Botulism, China Feces Feces - microbiology Food contamination Gastrointestinal Microbiome gut microbiome Hospitalization Hospitals Humans Infant Infant botulism Infants Infants (Newborn) Infectious diseases Intensive care Male Metabolism Metabolites Microbiota Pediatrics R&D Research & development Research Letter source-tracking targeted metabolomics Toxins Treatment Outcome
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Beschreibung
Zusammenfassung:	Infant botulism in a 4-month-old boy in China who continued to excrete toxins for over a month despite antitoxin therapy was further treated with fecal microbiota transplantation. After treatment, we noted increased gut microbial diversity and altered fecal metabolites, which may help reduce intestinal pH and enhance anti-inflammatory capabilities.
ISSN:	1080-6040 1080-6059 1080-6059
DOI:	10.3201/eid3008.231702