Impact of home blood pressure variability on cardiovascular outcome in patients with arterial stiffness: Results of the J‐HOP study

This study sought to investigate whether the relation between increased blood pressure (BP) variability and increased arterial stiffness confers a risk for cardiovascular disease (CVD) events. We analyzed 2648 patients from a practitioner‐based population (mean ± SD age 64.9 ± 11.4 years: 75.8% taki...

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Veröffentlicht in:	The journal of clinical hypertension (Greenwich, Conn.) Conn.), 2021-08, Vol.23 (8), p.1529-1537
Hauptverfasser:	Ishiyama, Yusuke, Hoshide, Satoshi, Kanegae, Hiroshi, Kario, Kazuomi
Format:	Artikel
Sprache:	eng
Schlagworte:	Aged Angina pectoris Ankle Brachial Index Antihypertensives arterial stiffness Blood Pressure Blood Pressure Variability brachial‐ankle pulse wave velocity Cardiovascular disease Cardiovascular Diseases - diagnosis Cardiovascular Diseases - epidemiology Cholesterol Diabetes Heart attacks home blood pressure Humans Hypertension - diagnosis Hypertension - drug therapy Hypertension - epidemiology Metabolic disorders Middle Aged Original Patients Population Pulse Wave Analysis Risk Factors Vascular Stiffness
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Beschreibung
Zusammenfassung:	This study sought to investigate whether the relation between increased blood pressure (BP) variability and increased arterial stiffness confers a risk for cardiovascular disease (CVD) events. We analyzed 2648 patients from a practitioner‐based population (mean ± SD age 64.9 ± 11.4 years: 75.8% taking antihypertensive medication) with at least one cardiovascular risk factor who underwent home BP monitoring in the Japan Morning Surge‐Home Blood Pressure Study. The standard deviation (SDSBP), coefficient of variation (CVSBP), and average real variability (ARVSBP) were assessed as indexes of day‐by‐day home systolic BP (SBP) variability. The authors assessed arterial stiffness by brachial‐ankle pulse wave velocity (baPWV) and divided patients into lower (
ISSN:	1524-6175 1751-7176
DOI:	10.1111/jch.14327