Antimicrobial activity of Hyptis ovalifolia towards dermatophytes

The essential oil and the aqueous, hexane and methanolic fractions from Hyptis ovalifolia leaves were evaluated for their antifungal activity in vitro against 60 strains of dermatophytes: 10 strains of Microsporum canis, 10 of M. gypseum, 20 of Trichophyton rubrum and 20 of T. mentagrophytes. The ex...

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Veröffentlicht in:	Memórias do Instituto Oswaldo Cruz 2003-10, Vol.98 (7), p.963-965
Hauptverfasser:	Souza, Lúcia K H, de Oliveira, Cecília M A, Ferri, Pedro H, de Oliveira Júnior, Juldásio Galdino, de Souza Júnior, Ary Henrique, Fernandes, Orionalda de Fátima Lisboa, Silva, Maria do Rosário R
Format:	Artikel
Sprache:	eng
Schlagworte:	antifungal activity Antifungal Agents - pharmacology Arthrodermataceae - classification Arthrodermataceae - drug effects Dermatophytes Dose-Response Relationship, Drug Hyptis Hyptis ovalifolia Microbial Sensitivity Tests Microsporum canis Microsporum gypseum PARASITOLOGY Plant Extracts - pharmacology Trichophyton mentagrophytes Trichophyton rubrum TROPICAL MEDICINE
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Zusammenfassung:	The essential oil and the aqueous, hexane and methanolic fractions from Hyptis ovalifolia leaves were evaluated for their antifungal activity in vitro against 60 strains of dermatophytes: 10 strains of Microsporum canis, 10 of M. gypseum, 20 of Trichophyton rubrum and 20 of T. mentagrophytes. The extracts inhibited growth of the dermatophytes tested at different concentrations. The most biologically active was the essential oil from the leaves which inhibited 57 isolates (95%) at a concentration of 500 g/ml.
ISSN:	0074-0276 1678-8060 0074-0276 1678-8060
DOI:	10.1590/S0074-02762003000700018