Effect of lymph node dissection on stage-specific survival in patients with upper urinary tract urothelial carcinoma treated with nephroureterectomy

We aimed to estimate the stage-specific impact of lymph node dissection (LND) on survival for upper urinary tract urothelial carcinoma (UTUC) patients treated with nephroureterectomy (NU). Overall, 7278 UTUC patients undergoing NU within the SEER database from 2004 to 2015 were identified. Kaplan-Me...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	BMC cancer 2019-12, Vol.19 (1), p.1207-1207, Article 1207
Hauptverfasser:	Zhai, Ting-Shuai, Jin, Liang, Zhou, Zhen, Liu, Xiang, Liu, Huan, Chen, Wei, Lu, Jing-Yi, Yao, Xu-Dong, Feng, Li-Ming, Ye, Lin
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Aged Aged, 80 and over Analysis Biopsy Bladder cancer Cancer Cancer staging Carcinoma Carcinoma, Transitional Cell - mortality Carcinoma, Transitional Cell - pathology Carcinoma, Transitional Cell - surgery Care and treatment Chemotherapy Datasets as Topic Disease Dissection Epidemiology Female Humans Lymph node dissection Lymph Node Excision - methods Lymph Node Excision - mortality Lymph nodes Lymph Nodes - pathology Lymph Nodes - surgery Lymphatic system Male Middle Aged Neoplasm Staging Nephroureterectomy - methods Nephroureterectomy - mortality Patient outcomes Regression analysis SEER Program Surgery Surveillance Survival Survival analysis Survival Rate Tumors United States - epidemiology Upper urinary tract urothelial carcinoma Ureteral Neoplasms - mortality Ureteral Neoplasms - pathology Ureteral Neoplasms - surgery Urinary tract Urogenital system Urologic Neoplasms - mortality Urologic Neoplasms - pathology Urologic Neoplasms - surgery Urothelial carcinoma Young Adult
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Beschreibung
Zusammenfassung:	We aimed to estimate the stage-specific impact of lymph node dissection (LND) on survival for upper urinary tract urothelial carcinoma (UTUC) patients treated with nephroureterectomy (NU). Overall, 7278 UTUC patients undergoing NU within the SEER database from 2004 to 2015 were identified. Kaplan-Meier plots illustrated overall survival (OS) and cancer-specific survival (CSS) rates according to LND status. Multivariable Cox regression analyses assessed the effect of LND on OS and CSS rates stratified by pathological tumor stage. LND was performed in 26.9% of patients, and in 18.6, 23.3, 31.2 and 45.9% for pT1, pT2, pT3 and pT4 patients, respectively (P
ISSN:	1471-2407 1471-2407
DOI:	10.1186/s12885-019-6364-z