Toward the prevention of coronavirus infection: what role can polymers play?
Severe acute respiratory syndrome–associated coronavirus 2 has caused a global public health crisis with high rates of infection and mortality. Treatment and prevention approaches include vaccine development, the design of small-molecule antiviral drugs, and macromolecular neutralizing antibodies. P...
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Veröffentlicht in: | Materials today advances 2021-06, Vol.10, p.100140-100140, Article 100140 |
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Format: | Artikel |
Sprache: | eng |
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Zusammenfassung: | Severe acute respiratory syndrome–associated coronavirus 2 has caused a global public health crisis with high rates of infection and mortality. Treatment and prevention approaches include vaccine development, the design of small-molecule antiviral drugs, and macromolecular neutralizing antibodies. Polymers have been designed for effective virus inhibition and as antiviral drug delivery carriers. This review summarizes recent progress and provides a perspective on polymer-based approaches for the treatment and prevention of coronavirus infection. These polymer-based partners include polyanion/polycations, dendritic polymers, macromolecular prodrugs, and polymeric drug delivery systems that have the potential to significantly improve the efficacy of antiviral therapeutics.
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ISSN: | 2590-0498 2590-0498 |
DOI: | 10.1016/j.mtadv.2021.100140 |