Bleeding and asymptomatic overdose in patients under Vitamin K antagonist therapy: Frequency and risk factors

Vitamin K antagonists are widely used in the treatment and prevention of thromboembolic disease. However, these drugs can cause serious side effects, especially bleeding. This study aims to evaluate frequency and risk factors of both bleeding and asymptomatic overdose in North African patients under...

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Veröffentlicht in:The Egyptian heart journal 2018-03, Vol.70 (1), p.45-49
Hauptverfasser: Ben Mbarka, F., Ben Jeddou, K., Allouche, E., Boukhris, I., Khalfallah, N., Baccar, H., Ouahchi, Z.
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Sprache:eng
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Zusammenfassung:Vitamin K antagonists are widely used in the treatment and prevention of thromboembolic disease. However, these drugs can cause serious side effects, especially bleeding. This study aims to evaluate frequency and risk factors of both bleeding and asymptomatic overdose in North African patients undergoing Vitamin K antagonist therapy. We performed a cross-sectional study in patients undergoing Vitamin K antagonist therapy. A statistical analysis has been conducted to identify overdose and bleeding risk factors by using chi-square test (p 
ISSN:1110-2608
2090-911X
DOI:10.1016/j.ehj.2018.01.001