Cu-Doped Carbon Dots as Catalysts for the Chemiluminescence Detection of Glucose
Development of metal-doped carbon dots (CDs) to effectively modulate their electronic properties and surface chemical reactivities is still in its early stage. In this paper, a facile solid-phase synthesis strategy was developed to synthesize Cu-doped CDs (Cu-CDs) using citric acid as the carbon sou...
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Veröffentlicht in: | ACS omega 2019-06, Vol.4 (6), p.9911-9917 |
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Hauptverfasser: | , , , , |
Format: | Artikel |
Sprache: | eng |
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Zusammenfassung: | Development of metal-doped carbon dots (CDs) to effectively modulate their electronic properties and surface chemical reactivities is still in its early stage. In this paper, a facile solid-phase synthesis strategy was developed to synthesize Cu-doped CDs (Cu-CDs) using citric acid as the carbon source and Cu(NO3)2·3H2O as the dopant, respectively. The as-prepared Cu-CDs exhibited superior peroxidase-like activity to horseradish peroxidase and were stable under a wide range of pH and temperatures. Consequently, the Cu-CD-based chemiluminescence sensing was applied to sensitively detect glucose with a low detection limit of 0.32 μM, and the recoveries and the relative standard deviation of the serum sample are 87.2–112.2 and 8.16% (n = 6), respectively. Notably, the proposed chemiluminescence sensing was also successfully applied for label-free detection of glucose in complex biological samples, which envisioned its potential applications in clinical diagnosis and other analytical assays. |
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ISSN: | 2470-1343 2470-1343 |
DOI: | 10.1021/acsomega.9b00738 |