3-(1-Ethylamino-ethylidene)-1-methyl-pyrrolidine-2,4-dione

3-(1-Ethylamino-ethylidene)-1-methyl-pyrrolidine-2,4-dione

3-(1-Ethylamino-ethylidene)-1-methyl-pyrrolidine-2,4-dione was obtained as an unexpected product in a three-step synthesis starting with o-nitrobenzoyl sarcosine, acetoacetanilide and ethylamine. The compound showed moderate antibacterial activity against S. aureus and E. coli.

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Bibliographische Detailangaben
Veröffentlicht in:MolBank 2023-01, Vol.2023 (1), p.M1556
Hauptverfasser: Angelov, Plamen, Terziyska, Paraskeva, Georgiev, Danail
Format: Artikel
Sprache:eng
Schlagworte:
Acetoacetanilides
Amines
Amino acids
Analysis
antibacterial
Antifungal agents
Chemical synthesis
Chromatography
Conflicts of interest
Cyclic compounds
E coli
enamine
Gram-positive bacteria
Identification and classification
Infrared spectroscopy
Methicillin
Methods
Nuclear magnetic resonance
Properties
pyrrolidine-2,4-dione
Reagents
Solvents
Staphylococcus aureus
tetramic acid
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Beschreibung
Zusammenfassung:3-(1-Ethylamino-ethylidene)-1-methyl-pyrrolidine-2,4-dione was obtained as an unexpected product in a three-step synthesis starting with o-nitrobenzoyl sarcosine, acetoacetanilide and ethylamine. The compound showed moderate antibacterial activity against S. aureus and E. coli.
ISSN:1422-8599
1422-8599
DOI:10.3390/M1556