Prognostic significance of systemic immune-inflammation index in triple-negative breast cancer

Prognostic significance of systemic immune-inflammation index in triple-negative breast cancer

The prognostic significance of the systemic immune-inflammation index (SII) in breast cancer is unknown. Here, we aimed to explore the connection between pretreatment SII and the survival of patients with triple-negative breast cancer (TNBC). We enrolled 160 TNBC patients treated in our hospital bet...

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Veröffentlicht in:Cancer management and research 2019-01, Vol.11, p.4471-4480
Hauptverfasser: Liu, Jingxin, Shi, Zhangzhen, Bai, Yuansong, Liu, Lin, Cheng, Kailiang
Format: Artikel
Sprache:eng
Schlagworte:
Immunity
Inflammation
Original Research
Prognosis
SII
Triple-negative breast cancer
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Zusammenfassung:The prognostic significance of the systemic immune-inflammation index (SII) in breast cancer is unknown. Here, we aimed to explore the connection between pretreatment SII and the survival of patients with triple-negative breast cancer (TNBC). We enrolled 160 TNBC patients treated in our hospital between May 2000 and June 2012. We employed the Kaplan-Meier curve and log-rank test to assess overall survival (OS), disease-free survival (DFS), and distant metastasis-free survival (DMFS). We identified the prognostic significance of SII using the Cox regression model. The Kaplan-Meier curve revealed the median OS as 44.2 and 82.4 months in high and low SII TNBC patients, respectively (
ISSN:1179-1322
1179-1322
DOI:10.2147/CMAR.S197623