Role of miR-100-5p and CDC25A in breast carcinoma cells

To inquiry about mechanism of miR-100-5p/CDC25A axis in breast carcinoma (BC), thus offering a new direction for BC targeted treatment. qRT-PCR was employed to explore miR-100-5p and CDC25A mRNA levels. Western blot was employed for detecting protein expression of CDC25A. Targeting relationship of m...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	PeerJ (San Francisco, CA) CA), 2022-01, Vol.9, p.e12263-e12263, Article e12263
Hauptverfasser:	Li, Xiaoping, Ren, Yanli, Liu, Donghong, Yu, Xi, Chen, Keda
Format:	Artikel
Sprache:	eng
Schlagworte:	Apoptosis Bioinformatics Biotechnology industry Breast cancer Breast carcinoma Cancer Carcinoma CDC25A Cell Biology Cell cycle Cell growth Cell migration Cell proliferation Cyclin-dependent kinases Genetics Kinases Medical prognosis Metastasis MicroRNAs Migration and invasion MiR-100-5p Molecular Biology mRNA Oncology Prognosis Proliferation Proteins RNA Software Survival analysis Women’s Health Wound healing
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Beschreibung
Zusammenfassung:	To inquiry about mechanism of miR-100-5p/CDC25A axis in breast carcinoma (BC), thus offering a new direction for BC targeted treatment. qRT-PCR was employed to explore miR-100-5p and CDC25A mRNA levels. Western blot was employed for detecting protein expression of CDC25A. Targeting relationship of miR-100-5p and CDC25A was verified by dual-luciferase assay. experiments were used for assessment of cell functions. In BC tissue and cells, miR-100-5p was significantly lowly expressed (
ISSN:	2167-8359 2167-8359
DOI:	10.7717/peerj.12263