Internal exposure of Chinese children from a typical coastal city to bisphenols and possible association with thyroid hormone levels

[Display omitted] •Eight bisphenols were detected in 345 children serum samples from a typical coastal city of China.•BPA remains the major bisphenol used in consumer products, and the major BPA alternatives were BPF and BPS.•Some individuals were suffering BPA exposure with higher or nearly equal t...

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Veröffentlicht in:Environment international 2021-11, Vol.156, p.106759-106759, Article 106759
Hauptverfasser: Guo, Cuicui, Ren, Feng, Jin, Jing, Zhang, He, Wang, Longxing, Zhang, Haijun, Chen, Jiping
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Sprache:eng
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Zusammenfassung:[Display omitted] •Eight bisphenols were detected in 345 children serum samples from a typical coastal city of China.•BPA remains the major bisphenol used in consumer products, and the major BPA alternatives were BPF and BPS.•Some individuals were suffering BPA exposure with higher or nearly equal the oral RfD.•The concentrations of serum bisphenol A are associated with serum TSH for the enthyroid children and hyperthyroid children, respectively. Bisphenols (BPs) are widely used in consumer products, and human exposure to BPs is nearly ubiquitous. However, human biomonitoring data are scarce, especially for children. In this study, we quantified eight BPs in the serum of 345 children from a typical coastal city in China. Bisphenol A (BPA), bisphenol F (BPF), and bisphenol S (BPS) were frequently detected (63% BPA, 68% BPF, 43% BPS), with geometric mean (GM) concentrations of 1.6, 0.08, and 0.04 ng/mL, respectively. The other five BPs had low detection frequencies (
ISSN:0160-4120
1873-6750
DOI:10.1016/j.envint.2021.106759