Metabolites Identification of Curcumin, Demethoxycurcumin and Bisdemethoxycurcumin in Rats After Oral Administration of Nanoparticle Formulations by Liquid Chromatography Coupled with Mass Spectrometry

Metabolites Identification of Curcumin, Demethoxycurcumin and Bisdemethoxycurcumin in Rats After Oral Administration of Nanoparticle Formulations by Liquid Chromatography Coupled with Mass Spectrometry

Background: Curcuminoids are promising cancer chemopreventive agents. Curcumin, demethoxycurcumin (DMC) and bisdemethoxycurcumin (BDMC) are the major bioactive curcuminoids in turmeric. However, comprehensive metabolic studies of these three curcuminoids are still limited.

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Veröffentlicht in:World Journal of Traditional Chinese Medicine 2016-12, Vol.2 (4), p.29-37
Hauptverfasser: Li, Rui, Wang, Qi, Fan, Jing-Ran, He, Jun-Bin, Qiao, Xue, Xiang, Cheng, Guo, De-An, Ye, Min
Format: Artikel
Sprache:eng
Schlagworte:
Bisdemethoxycurcumin
Curcumin
Demethoxycurcumin
Metabolic pathway
Solid lipid nanoparticles
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Zusammenfassung:Background: Curcuminoids are promising cancer chemopreventive agents. Curcumin, demethoxycurcumin (DMC) and bisdemethoxycurcumin (BDMC) are the major bioactive curcuminoids in turmeric. However, comprehensive metabolic studies of these three curcuminoids are still limited.
ISSN:2311-8571
2311-8571
DOI:10.15806/j.issn.2311-8571.2016.0035