PO.1.23 Thrombocytopenia as a predictor of systemic lupus erythematosus progression

PurposeThrombocytopenia is one of the most common hematological manifestations of SLE and some studies reveal, that this manifestation can be associated with specific organ involvement and higher disease activity. The aim of this study is to indicate differences between SLE patients with and without thrombocytopenia and also to find connections between the severity of thrombocytopenia and the titer of SLE specific antibodies.Methods61 patients with a mean age of 32 ± 6.1years and with 8.1 ± 4.7 years’ duration of SLE were enrolled in this study. All patients fulfilled with the EULAR/ACR 2019 classification criteria. Disease activity was measured with help of SLEDAI-2K score. ANA, Anti-dsDNA, Anti-Sm, APL antibodies, ESR, CRP were evaluated. Thrombocytopenia was graded as mild (100000–150000/μl), moderate(50000–100000/μl) and severe (