CLINICAL SIGNIFICANCE OF CYTOKINES SERUM LEVELS IN CHILDREN WITH CHICKEN POX

CLINICAL SIGNIFICANCE OF CYTOKINES SERUM LEVELS IN CHILDREN WITH CHICKEN POX

The serum levels of cytokines IL-1β, IL-8, IL-6, IFNα, IFNγ, IL-4, IL-10 were tested in ELISA in 74 children with different courses of chicken pox. Moderate severity course of chicken pox was accompanied by significant increase of IL-1β, IL-8, IFNα, IFNγ, IL-10 levels, but severe course of infection...

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Veröffentlicht in:Infekt͡s︡ii͡a︡ i immunitet 2015-04, Vol.5 (1), p.79-84
Hauptverfasser: Zheleznikova, G. F., Lobzin, Y. V., Skripchenko, N. V., Ivanova, G. P., Skripchenko, E. Y., Monakhova, N. E.
Format: Artikel
Sprache:eng ; rus
Schlagworte:
chicken pox
children
cytokines
varicella-zoster virus encephalitis
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Zusammenfassung:The serum levels of cytokines IL-1β, IL-8, IL-6, IFNα, IFNγ, IL-4, IL-10 were tested in ELISA in 74 children with different courses of chicken pox. Moderate severity course of chicken pox was accompanied by significant increase of IL-1β, IL-8, IFNα, IFNγ, IL-10 levels, but severe course of infection was associated with cytokine response reduction. Manifestation of varicella-zoster virus encephalitis was accompanied by the rise of IL-1β, IL-6, IFNγ and IL-10 levels during the second week of disease. 
ISSN:2220-7619
2313-7398
DOI:10.15789/2220-7619-2015-1-79-84