Fc fragment of immunoglobulin G receptor IIa (FCGR2A) as a new potential prognostic biomarker of esophageal squamous cell carcinoma

Fc fragment of immunoglobulin G receptor IIa (FCGR2A) as a new potential prognostic biomarker of esophageal squamous cell carcinoma

[...]a total of 3885 and 3477 DEGs were identified in dataset GSE130078 and GSE149609, respectively. [...]only 23 genes, including FCGR2A [Figure 1A], were found to be significantly and highly expressed in ESCC tissues compared with normal tissues [Supplementary Figure 1, http://links.lww.com/CM9/A7...

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Veröffentlicht in:Chinese medical journal 2021-11, Vol.135 (4), p.482-484
Hauptverfasser: Lu, Sifen, Li, Nan, Peng, Zhiqiang, Lu, Zuhong, Tu, Xingyue, Zhang, Wengeng, Kang, Yulin
Format: Artikel
Sprache:eng
Schlagworte:
Bioinformatics
Biomarkers
Chemokines
Correspondence
Cytokines
Esophageal cancer
Esophageal Neoplasms - pathology
Esophageal Squamous Cell Carcinoma - pathology
Gene expression
Genotype & phenotype
Humans
Immunoglobulin Fc Fragments
Immunoglobulins
Medical prognosis
Precision medicine
Prognosis
Proteins
Receptors, IgG
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Zusammenfassung:[...]a total of 3885 and 3477 DEGs were identified in dataset GSE130078 and GSE149609, respectively. [...]only 23 genes, including FCGR2A [Figure 1A], were found to be significantly and highly expressed in ESCC tissues compared with normal tissues [Supplementary Figure 1, http://links.lww.com/CM9/A768]. [...]compared with stage I, FCGR2A (F = 2.980, P = 0.033) [Figure 1C], FN1 (F = 4.840, P = 0.003) and SPP1 (F = 5.710, P 
ISSN:0366-6999
2542-5641
DOI:10.1097/CM9.0000000000001776