Bioactive assessment of the antioxidative and antidiabetic activities of oleanane triterpenoid isolates of sprouted quinoa yoghurt beverages and their anti-angiogenic effects on HUVECS line

[Display omitted] •1H NMR structural elucidation confirmed the isolated compounds as oleanolic acids.•Optimal antioxidative activities were observed at 24 h germination time.•OA extracts of QYB inhibited α-glucosidase and DPP-IV in a dose-dependent manner.•Germination optimized the cytotoxic effects of OA extracts of QYB.•The anti-angiogenic disruption of tubes formation was most prominent in OA of QY124. Oleanolic acid (OA), a pentacyclic triterpene was isolated from sprouted quinoa yoghurt beverage (QYB). The influence of sprouting on the antioxidative, antidiabetic and anti-angiogenic activities of the OA extracts were assessed. The results showed that all samples exhibited significant (p 0.05) reduced after OA treatment at ranges of 52.39–65.81%, 31.47–80.46%, and 22.84–43.22% in QY100, QY124 and QY172 respectively. Significant (p > 0.05) reductions in tube lengths and branches were also observed. Germination influenced the production of bioactive OA in QYB and therefore had dietary potentials of being effective against several cardiovascular-related diseases.