Therapy potential for the correction of cardiovascular disturbances in diabetes mellitus

Therapy potential for the correction of cardiovascular disturbances in diabetes mellitus

Aim. To study the dynamics of left ventricular (LV) structure and function, as well as vasomotor activity of arterial endothelium, in patients with Type 2 diabetes mellitus (DM-2) and diastolic heart failure (DHF) who are treated with an angiotensin II receptor antagonist olmesartan. Material and me...

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Veröffentlicht in:Kardiovaskuli͡a︡rnai͡a︡ terapii͡a︡ i profilaktika 2012-08, Vol.11 (4), p.59-64
Hauptverfasser: Tatarchenko, I. P., Pozdnyakova, N. V., Mordovina, A. G., Morozova, O. I., Rubleva, E. V.
Format: Artikel
Sprache:eng ; rus
Schlagworte:
angiotensin receptor antagonists
cardiac remodelling
diabetes mellitus
endothelial dysfunction
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Zusammenfassung:Aim. To study the dynamics of left ventricular (LV) structure and function, as well as vasomotor activity of arterial endothelium, in patients with Type 2 diabetes mellitus (DM-2) and diastolic heart failure (DHF) who are treated with an angiotensin II receptor antagonist olmesartan. Material and methods. The study included 56 patients (26 men and 30 women; mean age 58,2±5,3 years) with NYHA Functional Class I-II chronic heart failure (CHF), diastolic LV dysfunction (abnormal relaxation), and LV ejection fraction (EF) >50%. Other inclusion criteria were DM-2 duration
ISSN:1728-8800
2619-0125
DOI:10.15829/1728-8800-2012-4-59-64