Neuroticism trait and postnatal depression among Chinese women: the mediating role of childbirth experience and the moderating role of perceived social support

Despite the link between neuroticism trait and postnatal depression has been confirmed, little is known about the factors that influence this association. This study aimed to examine whether childbirth experience mediated the association between neuroticism trait and postnatal depression, and whether this indirect effect was moderated by perceived social support. A cross-sectional study was conducted with 1686 women within one year postpartum from 38 hospitals in China. Participants completed anonymous questionnaires measuring neuroticism trait, postnatal depression, childbirth experience, perceived social support, and demographic and obstetric variables. Data were analyzed using SPSS 26.0 and PROCESS 4.0. The prevalence of postnatal depression among Chinese women was 24.1%, higher than the global pooled prevalence. The results showed a positive correlation between neuroticism trait and postnatal depression, which was partially mediated by childbirth experience. The negative correlation between neuroticism trait and childbirth experience was moderated by perceived social support. Specifically, the negative impact of neuroticism trait on childbirth experience was stronger among women with high perceived social support. Our findings highlight the critical importance of interventions dedicated to improving the childbirth experience, which may help reduce postnatal depression. Moreover, neuroticism and perceived social support are highly correlated and must be considered simultaneously to inform individualized interventions for postnatal depression.