Interstitial pattern of cutaneous metastases and its diagnostic pitfalls: A report of three cases

Cutaneous metastases are rare and indicate a poor prognosis. Occasionally, these may be the only presenting sign, with clinically inapparent primary source of the malignancy. Of the various histologic patterns of cutaneous metastases, interstitial pattern is very uncommon and mimics inflammatory diseases such as granuloma annulare. This article illustrates three such cases and underscores the role of morphology and immunohistochemical markers in establishing the correct diagnosis.