A lyophilized colorimetric RT-LAMP test kit for rapid, low-cost, at-home molecular testing of SARS-CoV-2 and other pathogens

Access to fast and reliable nucleic acid testing continues to play a key role in controlling the COVID-19 pandemic, especially in the context of increased vaccine break-through risks due to new variants. We report a rapid, low-cost (~ 2 USD), simple-to-use nucleic acid test kit for self-administered...

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Veröffentlicht in:	Scientific reports 2022-04, Vol.12 (1), p.7043-7043, Article 7043
Hauptverfasser:	Song, Xin, Coulter, Felicity J., Yang, Ming, Smith, Jessica L., Tafesse, Fikadu G., Messer, William B., Reif, John H.
Format:	Artikel
Sprache:	eng
Schlagworte:	631/1647 631/326/2521 631/45 631/61 692/699/255 Colorimetry Colorimetry - methods COVID-19 COVID-19 - diagnosis Freeze drying Gene amplification Humanities and Social Sciences Humans Infectious diseases Instrumentation Molecular Diagnostic Techniques multidisciplinary Nucleic Acid Amplification Techniques Nucleic Acids Pandemics Pathogens Public health Reagents SARS-CoV-2 - genetics Science Science (multidisciplinary) Sensitivity and Specificity Severe acute respiratory syndrome coronavirus 2
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Beschreibung
Zusammenfassung:	Access to fast and reliable nucleic acid testing continues to play a key role in controlling the COVID-19 pandemic, especially in the context of increased vaccine break-through risks due to new variants. We report a rapid, low-cost (~ 2 USD), simple-to-use nucleic acid test kit for self-administered at-home testing without lab instrumentation. The entire sample-to-answer workflow takes
ISSN:	2045-2322 2045-2322
DOI:	10.1038/s41598-022-11144-5