In Vivo Phenotyping of Tumor Metabolism in a Canine Cancer Patient with Simultaneous 18F-FDG-PET and Hyperpolarized 13C-Pyruvate Magnetic Resonance Spectroscopic Imaging (hyperPET): Mismatch Demonstrates that FDG may not Always Reflect the Warburg Effect

In Vivo Phenotyping of Tumor Metabolism in a Canine Cancer Patient with Simultaneous 18F-FDG-PET and Hyperpolarized 13C-Pyruvate Magnetic Resonance Spectroscopic Imaging (hyperPET): Mismatch Demonstrates that FDG may not Always Reflect the Warburg Effect

In this communication the mismatch between simultaneous 18F-FDG-PET and a 13C-lactate imaging (hyperPET) in a biopsy verified squamous cell carcinoma in the right tonsil of a canine cancer patient is shown. The results demonstrate that 18F-FDG-PET may not always reflect the Warburg effect in all tum...

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Veröffentlicht in:Diagnostics (Basel) 2015-06, Vol.5 (3), p.287-289
Hauptverfasser: Gutte, Henrik, Hansen, Adam, Larsen, Majbrit, Rahbek, Sofie, Johannesen, Helle, Ardenkjaer-Larsen, Jan, Kristensen, Annemarie, Højgaard, Liselotte, Kjaer, Andreas
Format: Artikel
Sprache:eng
Schlagworte:
13C-pyruvate
18F-FDG-PET
Cancer
Dogs
dynamic nuclear polarization
Genotype & phenotype
hyperPET
hyperpolarized
Interesting Images
Metabolism
molecular imaging
PET/MR
Tomography
Veterinary medicine
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Zusammenfassung:In this communication the mismatch between simultaneous 18F-FDG-PET and a 13C-lactate imaging (hyperPET) in a biopsy verified squamous cell carcinoma in the right tonsil of a canine cancer patient is shown. The results demonstrate that 18F-FDG-PET may not always reflect the Warburg effect in all tumors.
ISSN:2075-4418
2075-4418
DOI:10.3390/diagnostics5030287