Carbonic Anhydrases III and IV Autoantibodies in Rheumatoid Arthritis, Systemic Lupus Erythematosus, Diabetes, Hypertensive Renal Disease, and Heart Failure

In the present study, the CA III and IV autoantibodies, CA activity, antioxidant enzymes and cytokines in rheumatoid arthritis (RA), systemic lupus erythematosus (SLE), diabetes, hypertensive renal disease, and heart failure were investigated. The anti-CA III antibody titers in patients with RA, SLE...

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Veröffentlicht in:	Clinical & developmental immunology 2012-01, Vol.2012 (2012), p.1-6
Hauptverfasser:	Liu, Chengeng, Wei, Yue, Wang, Jianmin, Pi, Langan, Huang, Jianjun, Wang, Peichang
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Age Aged Antioxidants Antioxidants - metabolism Arthritis Arthritis, Rheumatoid - immunology Arthritis, Rheumatoid - metabolism Autoantibodies Autoantibodies - immunology Autoimmune diseases Autoimmunity Carbon dioxide Carbonate dehydratase Carbonic Anhydrase III - immunology Carbonic Anhydrase III - metabolism Carbonic Anhydrase IV - immunology Carbonic Anhydrase IV - metabolism Clinical Study Cytokines Diabetes Diabetes mellitus Diabetes Mellitus, Type 1 - immunology Diabetes Mellitus, Type 1 - metabolism Diabetes therapy Diabetic nephropathies Disease Enzymes Female Free radicals gamma -Interferon Heart diseases Heart failure Heart Failure - immunology Heart Failure - metabolism Hospitals Humans Hypertension Hypertension, Renal - immunology Hypertension, Renal - metabolism Immune system Immunity Immunology Interferon-gamma - immunology Interferon-gamma - metabolism Interleukin 17 Interleukin 6 Interleukin-17 - immunology Interleukin-17 - metabolism Interleukin-6 - immunology Interleukin-6 - metabolism Kidney diseases Lupus Lupus Erythematosus, Systemic - immunology Lupus Erythematosus, Systemic - metabolism Male Middle Aged Nephritis - immunology Nephritis - metabolism Nephropathy Physiological aspects Rheumatoid arthritis Rodents Superoxide dismutase Superoxide Dismutase - immunology Superoxide Dismutase - metabolism Systemic lupus erythematosus Tumor necrosis factor- alpha Tumor Necrosis Factor-alpha - immunology Tumor Necrosis Factor-alpha - metabolism Type 1 diabetes
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Zusammenfassung:	In the present study, the CA III and IV autoantibodies, CA activity, antioxidant enzymes and cytokines in rheumatoid arthritis (RA), systemic lupus erythematosus (SLE), diabetes, hypertensive renal disease, and heart failure were investigated. The anti-CA III antibody titers in patients with RA, SLE, and type 1 diabetes (T1D) were significantly higher than that in control groups (P
ISSN:	1740-2522 2314-8861 1740-2530 2314-7156
DOI:	10.1155/2012/354594