Selection of single blastocysts for fresh transfer via standard morphology assessment alone and with array CGH for good prognosis IVF patients: results from a randomized pilot study

Selection of single blastocysts for fresh transfer via standard morphology assessment alone and with array CGH for good prognosis IVF patients: results from a randomized pilot study

Single embryo transfer (SET) remains underutilized as a strategy to reduce multiple gestation risk in IVF, and its overall lower pregnancy rate underscores the need for improved techniques to select one embryo for fresh transfer. This study explored use of comprehensive chromosomal screening by arra...

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Veröffentlicht in:Molecular cytogenetics 2012-05, Vol.5 (1), p.24-24, Article 24
Hauptverfasser: Yang, Zhihong, Liu, Jiaen, Collins, Gary S, Salem, Shala A, Liu, Xiaohong, Lyle, Sarah S, Peck, Alison C, Sills, E Scott, Salem, Rifaat D
Format: Artikel
Sprache:eng
Schlagworte:
Analysis
Blastocyst
Chromosomes
Cytogenetics
Fertilization in vitro
Genetic aspects
Health aspects
Methodology
Physiological aspects
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Zusammenfassung:Single embryo transfer (SET) remains underutilized as a strategy to reduce multiple gestation risk in IVF, and its overall lower pregnancy rate underscores the need for improved techniques to select one embryo for fresh transfer. This study explored use of comprehensive chromosomal screening by array CGH (aCGH) to provide this advantage and improve pregnancy rate from SET. First-time IVF patients with a good prognosis (age
ISSN:1755-8166
1755-8166
DOI:10.1186/1755-8166-5-24