Nutritional status affects immune function and exacerbates the severity of pulmonary tuberculosis

Nutritional status affects immune function and exacerbates the severity of pulmonary tuberculosis

To comprehensively evaluate the association and impact of nutritional status and immune function on the severity of pulmonary tuberculosis (PTB). This descriptive cross-sectional study involved 952 participants who were diagnosed with active PTB. Severe PTB involves three or more lung field infectio...

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Veröffentlicht in:Frontiers in immunology 2024-07, Vol.15, p.1407813
Hauptverfasser: Lu, Chunli, Xu, Yunyi, Li, Xueya, Wang, Min, Xie, Bei, Huang, Yaling, Li, Yan, Fan, Jiahua
Format: Artikel
Sprache:eng
Schlagworte:
Adult
Aged
BMI
Body Mass Index
Cross-Sectional Studies
Female
Humans
immune function
Immunology
Male
mediation
Middle Aged
Neutrophils - immunology
Nutrition Assessment
Nutritional Status
pulmonary tuberculosis (PTB)
Risk Factors
Severity of Illness Index
Tuberculosis, Pulmonary - immunology
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Zusammenfassung:To comprehensively evaluate the association and impact of nutritional status and immune function on the severity of pulmonary tuberculosis (PTB). This descriptive cross-sectional study involved 952 participants who were diagnosed with active PTB. Severe PTB involves three or more lung field infections based on chest radiography. Nutritional status was evaluated using various indicators, including body mass index (BMI), the nutritional risk screening score (NRS-2002), total protein (TP), prealbumin (PA), transferrin (TRF), and serum albumin (ALB) levels and the prognostic nutritional index (PNI). Immune dysfunction was defined as a CD4 count
ISSN:1664-3224
1664-3224
DOI:10.3389/fimmu.2024.1407813