Investigation of the migration of bisphenols from baby bottles and sippy cups

Bisphenol A (BPA) is used as a monomer in a number of consumer products, including baby bottles and sippy cups. Some jurisdictions around the world (including Canada) have regulated the production, advertising or selling polycarbonate baby bottles with BPA. Following the ban, makers have opted for alternative materials to BPA [named BPA analogues, BPAAs], which may not be as safe as promoted. The objective of this project was to conduct a migration study in baby bottles and sippy cups, and analyze 16 BPAAs, as a follow-up on the BPA migration study conducted by Health Canada in 2009. Baby bottles (20 brands) and sippy cups (13 brands) were tested for migration of BPAAs. The most commonly detected analytes in baby bottles were BPS, BPA, BPF, BPAF, BPM and BPTMC with detection frequency (DF) of more than 50%. In sippy cups, only BPA, BPS and BPF were frequently detected. The mean concentration of BPA in baby bottle leachate was 31.5 ng/L in water simulant whereas a 1.4-fold increase was seen in 50% EtOH simulant. Similarly, a 1.4-fold increase was seen in the mean concentration of BPS in 50% EtOH simulant, when compared to the mean concentration of 2.33 ng/L in water simulant. Increasing median concentration was observed for BPA as the ethanol content of the simulant increased (water