Selenium supplementation in patients with peripartum cardiomyopathy: a proof-of-concept trial

We studied the efficacy and safety of selenium supplementation in patients who had peripartum cardiomyopathy (PPCM) and selenium deficiency. We randomly assigned 100 PPCM patients with left ventricular ejection fraction (LVEF)

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Bibliographische Detailangaben
Veröffentlicht in:	BMC cardiovascular disorders 2020-10, Vol.20 (1), p.457-10, Article 457
Hauptverfasser:	Karaye, Kamilu M, Sa'idu, Hadiza, Balarabe, Suleiman A, Ishaq, Naser A, Sanni, Bushra, Abubakar, Haruna, Mohammed, Baba Lawan, Abdulsalam, Tijjani, Tukur, Jamilu, Mohammed, Idris Y
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Cardiomyopathies - diagnosis Cardiomyopathies - drug therapy Cardiomyopathies - mortality Cardiomyopathies - physiopathology Cardiomyopathy Care and treatment Clinical outcomes Congestive heart failure Deficiency Diseases - diagnosis Deficiency Diseases - drug therapy Deficiency Diseases - mortality Deficiency Diseases - physiopathology Dietary supplements Dietary Supplements - adverse effects Enzymes Female Heart Failure - diagnosis Heart Failure - drug therapy Heart Failure - mortality Heart Failure - physiopathology Humans Laboratories Mortality Myocardial diseases Nigeria Outcomes Patient safety PEACE registry Peripartum cardiomyopathy Peripartum Period Pregnancy Proof of Concept Study Prospective Studies Puerperal disorders Puerperal Disorders - diagnosis Puerperal Disorders - drug therapy Puerperal Disorders - mortality Puerperal Disorders - physiopathology Selenium Selenium (Nutrient) Selenium - deficiency Selenium supplementation Selenomethionine Selenomethionine - adverse effects Selenomethionine - therapeutic use Statistical analysis Stroke Volume - drug effects Teaching hospitals Testing Time Factors Treatment Outcome Ventricle Ventricular Function, Left - drug effects Young Adult
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Beschreibung
Zusammenfassung:	We studied the efficacy and safety of selenium supplementation in patients who had peripartum cardiomyopathy (PPCM) and selenium deficiency. We randomly assigned 100 PPCM patients with left ventricular ejection fraction (LVEF)
ISSN:	1471-2261 1471-2261
DOI:	10.1186/s12872-020-01739-z