THE ROLE OF OVARIAN SUPPRESSION IN THE TREATMENT OF EARLY-STAGE HORMONE-SENSITIVE BREAST CANCER

THE ROLE OF OVARIAN SUPPRESSION IN THE TREATMENT OF EARLY-STAGE HORMONE-SENSITIVE BREAST CANCER

Ovarian suppression (OS) is an effective method of treating hormone sensitive breast cancer. The combination of OS and tamoxifen in breast cancer is more effective than any of these methods used as monotherapy. A number of clinical trials confirmed the need for OS chemotherapy in patients with hormo...

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Veröffentlicht in:Opukholi zhenskoĭ reproduktivnoĭ sistemy 2018-08, Vol.14 (2), p.54-60
Hauptverfasser: Koroleva, I. A., Kopp, M. V.
Format: Artikel
Sprache:eng ; rus
Schlagworte:
breast cancer
exemestane
gonadotropin-releasing hormone analogues
hormone therapy
ovarian suppression
tamoxifen
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Zusammenfassung:Ovarian suppression (OS) is an effective method of treating hormone sensitive breast cancer. The combination of OS and tamoxifen in breast cancer is more effective than any of these methods used as monotherapy. A number of clinical trials confirmed the need for OS chemotherapy in patients with hormone-positive operable breast cancer, because women retained their menstrual function for 5 years. OS chemotherapy during adjuvant chemotherapy allows preserving fertility in patients with breast cancer.
ISSN:1994-4098
1999-8627
DOI:10.17650/1994-4098-2018-14-2-54-60