Data on docking of phytoconstituents of Actinidia deliciosa on dengue viral targets

Data on docking of phytoconstituents of Actinidia deliciosa on dengue viral targets

Major Phytoconstituents of Actinidia deliciosa were explored for their anti-viral potential against dengue virus (DENV). The docking of these phytoconstituents was performed on 7 viral targets- 4 DENV non structural protein (NS5-SAM binding domain, NS5 RdRp domain, NS3 helicase & NS2B-NS3 protea...

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Veröffentlicht in:Data in brief 2019-08, Vol.25, p.103996-103996, Article 103996
Hauptverfasser: Chandani, Sneha R., Lokhande, Kiran B., Swamy, K. Venkateswara, Nanda, Rabindra K., Chitlange, Sohan S.
Format: Artikel
Sprache:eng
Schlagworte:
Actinidia
Apigenin
Dengue
Docking
Luteolin
Pharmacology, Toxicology and Pharmaceutical Science
Targets
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Zusammenfassung:Major Phytoconstituents of Actinidia deliciosa were explored for their anti-viral potential against dengue virus (DENV). The docking of these phytoconstituents was performed on 7 viral targets- 4 DENV non structural protein (NS5-SAM binding domain, NS5 RdRp domain, NS3 helicase & NS2B-NS3 protease) and 3 DENV structural proteins (Envelope protein-β-OD domain, stem domain & Domain III). The analysis was done on the basis of binding affinity, type of interactions (bond type and distance) and interaction with amino acids significant in viral replication. The top 5 phytoconstituents with best docking score have been reported.
ISSN:2352-3409
2352-3409
DOI:10.1016/j.dib.2019.103996