Easing the way to achieving target serum urate in people with gout: protocol for a non-inferiority randomised strategy trial using an allopurinol dosing model in Aotearoa/New Zealand (the Easy-Allo Study)

IntroductionGout is one of the most common forms of arthritis worldwide. Gout is particularly prevalent in Aotearoa/New Zealand and is estimated to affect 13.1% of Māori men, 22.9% of Pacific men and 7.4% of New Zealand European men. Effective long-term treatment requires lowering serum urate to

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Veröffentlicht in:	BMJ open 2024-08, Vol.14 (8), p.e084665
Hauptverfasser:	Stamp, Lisa, Te Karu, Leanne, Reid, Susan, Wright, Daniel F B, Frampton, Chris, Tuitaupe, Vui Suli, Dalbeth, Nicola
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Allopurinol - administration & dosage Allopurinol - therapeutic use Arthritis Best practice Blood tests Clinical Trial Clinical trials Dose-Response Relationship, Drug Equivalence Trials as Topic Female Gout - blood Gout - drug therapy Gout Suppressants - administration & dosage Gout Suppressants - therapeutic use Humans Intervention Male New Zealand Protocol Rheumatology Uric Acid - blood
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Zusammenfassung:	IntroductionGout is one of the most common forms of arthritis worldwide. Gout is particularly prevalent in Aotearoa/New Zealand and is estimated to affect 13.1% of Māori men, 22.9% of Pacific men and 7.4% of New Zealand European men. Effective long-term treatment requires lowering serum urate to
ISSN:	2044-6055 2044-6055
DOI:	10.1136/bmjopen-2024-084665