AGROBACTERIUM TUMEFACIENS FA2 SENSITIVITY ТО THE SYNTHETIC PORPHYRINS ACTION

Dark and photoinduced action of new synthetic porphyrins with different molecular charges has been studied towards plant bacterial cancer agent Agrobacterium tumefaciens. It has been shown that cation porphyrins are most effective upon both dark condition and photoactivation. The most active compounds in this group are asymmetric substituded porphyrins, with n-nonyl in one of meso-positions. They caused almost total photoactivated inhibition of a. tumefaciens growth. Under dark conditions these porphyrins also have bactericidal effect. The death of A. tumefaciens cells probably occurs as the result of important metabolic function inhibition.