The role of sialidase Neu1 in respiratory diseases

Neu1 is a sialidase enzyme that plays a crucial role in the regulation of glycosylation in a variety of cellular processes, including cellular signaling and inflammation. In recent years, numerous evidence has suggested that human NEU1 is also involved in the pathogenesis of various respiratory dise...

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Veröffentlicht in:	Respiratory research 2024-03, Vol.25 (1), p.134-134, Article 134
Hauptverfasser:	Mei, Shiran, Li, Dingding, Wang, Aoyi, Zhu, Guoxue, Zhou, Bingwen, Li, Nian, Qin, Yi, Zhang, Yanliang, Jiang, Shujun
Format:	Artikel
Sprache:	eng
Schlagworte:	Analysis Angiogenesis Asthma Bacterial infections Bronchopulmonary infection Cancer Care and treatment Chronic infection Chronic obstructive pulmonary disease Diagnosis Enzymes Extracellular matrix Fibrosis Glycosylation Health aspects Humans Infections Inflammation Kinases Lung diseases Lungs Neuraminidase - genetics Pathogenesis Pulmonary fibrosis Respiration Disorders Respiratory diseases Respiratory disorders Review Risk factors Sialic acids Smooth muscle Tumors
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Beschreibung
Zusammenfassung:	Neu1 is a sialidase enzyme that plays a crucial role in the regulation of glycosylation in a variety of cellular processes, including cellular signaling and inflammation. In recent years, numerous evidence has suggested that human NEU1 is also involved in the pathogenesis of various respiratory diseases, including lung infection, chronic obstructive pulmonary disease (COPD), asthma, and pulmonary fibrosis. This review paper aims to provide an overview of the current research on human NEU1 and respiratory diseases.
ISSN:	1465-993X 1465-9921 1465-993X 1465-9921
DOI:	10.1186/s12931-024-02763-9