Search of intravascular hemolysis in patients with the cutaneous form of loxoscelism Pesquisa de hemólise intravascular na forma cutânea de loxoscelismo

Haptoglobin assay, a highly sensitive method to detect intravascular hemolysis was carried out in the sera of 19 patients referred to Hospital Vital Brazil with the cutaneous form of loxoscelism in order to investigate the occurrence of mild intravascular hemolysis. Data from this series did not sho...

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Veröffentlicht in:Revista do Instituto de Medicina Tropical de São Paulo 1994-04, Vol.36 (2), p.149-151
Hauptverfasser: Pasquale Morena, Kimiyo Nonoyama, João Luiz C. Cardoso, Orlando C. de O. Barreto
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Sprache:eng
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Zusammenfassung:Haptoglobin assay, a highly sensitive method to detect intravascular hemolysis was carried out in the sera of 19 patients referred to Hospital Vital Brazil with the cutaneous form of loxoscelism in order to investigate the occurrence of mild intravascular hemolysis. Data from this series did not show decreased levels haptoglobin, ruling out intravascular hemolysis in these patients with cutaneous form of loxoscelism.Dezenove pacientes que apresentaram a forma clínica cutânea do loxoscelismo foram investigados com o propósito de pesquisar hemólise intravascular sub-clínica, lançando mão da dosagem de haptoglobina, um método altamente sensível que permite detectar discreta presença de hemólise intravascular. Não foi encontrada diminuição de haptoglobina, o que descarta uma ação hemolítica do veneno da Loxosceles nestes pacientes.
ISSN:0036-4665
1678-9946
DOI:10.1590/S0036-46651994000200009